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Haemophilia
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Paris M
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Joined: 24 Sep 2009
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PostPosted: Tue Oct 06, 2009 9:11 pm    Post subject: Haemophilia Reply with quote

I was reading up on Brittany health issues and came across a reference to Haemophilia occuring in the breed. I wondered how many dogs are currently affected by this in the UK or if anyone is currently testing breeding dogs that may carry the gene. I understand, from what I have read, that if one mates a carrier to a carrier, then half of the male pups born would have haemophilia Question  Exclamation  Correct me if I am wrong. I looked through the previous threads but there doesn't seem to be one about this particular issue.
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guy
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PostPosted: Tue Oct 06, 2009 9:35 pm    Post subject: Reply with quote

http://www.thekennelclub.org.uk/download/1528/hsbrittany.pdf

is the best I can offer for the UK.
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Paris M
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PostPosted: Tue Oct 06, 2009 10:03 pm    Post subject: Reply with quote

Thanks that made interesting reading
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doganjo
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Joined: 26 Aug 2008
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Location: scotland

PostPosted: Tue Oct 06, 2009 10:11 pm    Post subject: Reply with quote

Never heard of this in our breed.  Why don't you ask our health co-ordinator.

I can't see this disease mentioned in this report.  Can you tell me where it is?  Where did you find a reference to this disease being in our breed?

These reports were commissioned and published on the KC website in 2006, and this one carries this disclaimer
Quote:
"Warning: The results of this survey and particularly the breed-specific analyses
should be interpreted with caution. The overall response rate was
only 24%
with breed-specific response rates from 4.5% to 64.7%."


Quote:
A total of 225 forms were sent out and 59 were returned, representing 113 live dogs.


Of the 59 how many mentioned haemophilia?
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Paris M
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Joined: 24 Sep 2009
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PostPosted: Wed Oct 07, 2009 11:34 am    Post subject: Reply with quote

The reference was not in that report that Guy posted the link to. I said it was interesting not because the report contained haemophilia, it doesn't, but becuase it was just interesting full stop. The reference came from an american published book on Brittanys I own.
Quote:
Other hereditary Conditions
Several other hereditary diseases are reported to occur in the Brittany in medical and Genetic aspects of pure-bred Dogs. They include haemophilia A (Factor VIII or antihemophilic factor deficiency) which causes prolonged bleeding, luxating patellas, overbite, underbite, and lip fold dermatitis.


The website that I found with a reference to Haemophilia is of uk origin. It seems to make reference to UK Brits with regards to hip displaysia but I think they are also using information gathered from US studies.  Scroll down to find Brittany, it is in the section begining Heart and Circulatory systems.
http://anti-dockingalliance.co.uk/gundog_12.htm
Of course the information seems to be reflective of American health studies and the American brits. Its just out of curiousity I'm asking, it seems however that from the responses that it is not a problem in the UK Brits (yay  Very Happy ).
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doganjo
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PostPosted: Wed Oct 07, 2009 2:26 pm    Post subject: Reply with quote

Well, in 27 years in the breed (since they were brought into the UK), I have heard of no instances in French Bred Brittanys in the UK.  So I think it must be solely in the American Brittany.  I certainly hope so.
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Ghilliegumdrop
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PostPosted: Wed Oct 07, 2009 4:40 pm    Post subject: Reply with quote

And GSD's.
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Wyngold
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PostPosted: Thu Oct 08, 2009 5:21 pm    Post subject: Reply with quote

Reference to blood disorders in Brittanys in various books is statistical data collected from around the world.  TRhere are "French" lined dogs and others with these conditions reported just luckily none reported thus far in the UK apparently.

Also some blood clotting issues are also a product of immune responses to hypervaccination protocols.  Low platelets have aslo been associated to Low Thyroid function. French dogs definatley do have problems with as well and Immune digestive disorders associated with Protien loosing enteropathy (diarrhea syndroms/malabsorptions) French dogs are prone to neurological and musculoskelatal problems as well most notable is cerebellar dysfunctions often associated with a prancing gait in the front limbs that later degenerate into ataxia often passed off as old age.   Might be associated to somee of the "setter" genes since Gordons are highly affected with Cerebellar ataxia as well.

I had one vet in Idaho tell a French owner that their dog had Factor 8 defficiencey but we figured out that he dog had gotten a hold of Rat poison and was not treated nor diagnosed properly.   There seems to be lots of blindness issues associated with early onset PRA in Euro lines and in American lines we seem to have late onset PRA which tells us that the lines on either side fo the pond have many differing genes pools.

Looking at the collective report that Guy linked to is classical on how poor a response one gets form these kinds of information research....failure to respond can be taken that someone wishes to hide information or they just do not care.  We get low turn out response to our breed surveys as well in the US so it seems that accurate data is very hard to collect.  Probalby the best place to find health data is in Sweden where all health issues are reported by law.
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glynis
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PostPosted: Sun Oct 11, 2009 7:36 pm    Post subject: Reply with quote

Goldie, could you post more information about PRA/gPRA in the breed please?
thanks
GLynis
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Wyngold
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PostPosted: Sun Oct 11, 2009 8:10 pm    Post subject: Reply with quote

glynis wrote:
Goldie, could you post more information about PRA/gPRA in the breed please?
thanks
GLynis


Well if you read the France forum in French...there have been several cases where buyers of pups reported that the pups they got were or arrived "Blind" this is strognly associated with Retinal detachment or "early onset" PRA.    In American lines we have been testing for a while now and there are specific lines that have shown the Late onset usually they go blind at around age 8 yrs this is the Rod/Cone form or late onset PRA.

If yu visit the Brittany health foundation pages I am not sure if it is posted there or not but also on the AKC canine health foundation pages it specifies that researchers have concluded that Cataracts are also genetically linked to PRA.  So "our old dog ailments" are really still genetic disorders that we are not really screening for or looking at as best we should.

Amny Brittany owners have said and re-tell that Brittanys are relatively healthy...they are to those that have never seen or heard of them.  Keep an open ear and you will learn much all around inthe breed.  I know that many like to call Lens Luxations as being a "field" accident but in reality Brittanys are also genetically prone to this condition due to week attachments or the dreaded precursor of cataracts.


Basically if you assume you don;t have issues and never screen for them "Of course you will never find them"

This is a Veterinary guide to some notable and have been seen conditions in purbred dogs which will give you some information:

http://www.upei.ca/~cidd/Diseases...ogressive%20Retinal%20Atrophy.htm



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